Endobiotics glucuronidation: a novel therapeutic avenue for metabolic and endocrine diseases

内生素葡萄糖醛酸化：代谢和内分泌疾病的新治疗途径

• 批准号: 172371
• 负责人: Barbier Olivier
• 金额: $ 21.86万
• 依托单位: Universit Laval
• 依托单位国家: 加拿大
• 项目类别: Salary Programs
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-09-01 至 2013-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=172371&lang=en
• 关键词: Cardiovascular Diseases; Endobiotics Metabolism; Gene Regulation; Hormonal Diseases; Liver Diseases; Molecular Pharmacology

Glucuronidation is an enzymatic reaction very well studied for the role its plays in drug elimination. However, this reaction also affects a wide variety of endogenous substance. The aim of our research program is to determine whether controlling the elim

葡萄糖醛酸化是一种酶促反应，因其在药物消除中的作用而得到充分研究。然而，这种反应也会影响多种内源性物质。我们研究计划的目的是确定控制埃利姆是否