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The role of glycosphingolipids in the secretion and clearance of extracellular vesicles in brain health and disease

The role of glycosphingolipids in the secretion and clearance of extracellular vesicles in brain health and disease
鞘糖脂在脑健康和疾病中细胞外囊泡的分泌和清除中的作用
批准号:
433798
负责人:
Sipione Simonetta
金额:
$75.79万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2020
资助国家:
加拿大
项目状态:
未结题
起止时间:
2020-10-01 至 2025-10-01

项目摘要

项目成果

Sipione Simonetta的其他基金

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中文摘要
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英文摘要
Gangliosides are lipid molecules highly enriched in the healthy brain that play important roles in the communication among cells. During ageing and in certain neurodegenerative diseases, levels of gangliosides decrease and contribute to brain dysfunction.
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A novel role for lipid droplets in proteostasis: Implications for misfolded protein diseases of the nervous system
  • 批准号:
    468690
  • 项目类别:
    Operating Grants
  • 资助金额:
    $71.06万
  • 财政年份:
    2022
  • 负责人:
    Sipione Simonetta
  • 依托单位:
Development of ganglioside-based therapies for Huntington's disease
  • 批准号:
    231670
  • 项目类别:
    Operating Grants
  • 资助金额:
    $11.6万
  • 财政年份:
    2011
  • 负责人:
    Sipione Simonetta
  • 依托单位:
Cellular lipids in Huntington's disease
  • 批准号:
    241199
  • 项目类别:
    Operating Grants
  • 资助金额:
    $0.0万
  • 财政年份:
    2011
  • 负责人:
    Sipione Simonetta
  • 依托单位:
CANADA RESEARCH CHAIRHOLDER / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA
  • 批准号:
    256327
  • 项目类别:
  • 资助金额:
    $36.43万
  • 财政年份:
    2011
  • 负责人:
    Sipione Simonetta
  • 依托单位: