课题基金 / 基金详情

A novel role for lipid droplets in proteostasis: Implications for misfolded protein diseases of the nervous system

A novel role for lipid droplets in proteostasis: Implications for misfolded protein diseases of the nervous system
脂滴在蛋白质稳态中的新作用:对神经系统错误折叠蛋白质疾病的影响
批准号:
468690
负责人:
Sipione Simonetta
金额:
$71.06万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-09-01 至 2027-09-01

项目摘要

项目成果

Sipione Simonetta的其他基金

相似基金

相关文献

中文摘要
翻译
形状异常(错误折叠)的有毒蛋白质会随着年龄的增长在大脑中积累,并在许多神经退行性疾病(包括亨廷顿氏病、帕金森病和阿尔茨海默病)中积累,从而引发细胞压力。健康的细胞有许多细胞
英文摘要
Toxic proteins with abnormal shapes (misfolded) accumulate in the brain as we age and in many neurodegenerative disorders, including Huntington's disease, Parkinson's disease and Alzheimer's disease, inducing cellular stress. Healthy cells have many strat
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
The role of glycosphingolipids in the secretion and clearance of extracellular vesicles in brain health and disease
  • 批准号:
    433798
  • 项目类别:
    Operating Grants
  • 资助金额:
    $75.79万
  • 财政年份:
    2020
  • 负责人:
    Sipione Simonetta
  • 依托单位:
Development of ganglioside-based therapies for Huntington's disease
  • 批准号:
    231670
  • 项目类别:
    Operating Grants
  • 资助金额:
    $11.6万
  • 财政年份:
    2011
  • 负责人:
    Sipione Simonetta
  • 依托单位:
Cellular lipids in Huntington's disease
  • 批准号:
    241199
  • 项目类别:
    Operating Grants
  • 资助金额:
    $0.0万
  • 财政年份:
    2011
  • 负责人:
    Sipione Simonetta
  • 依托单位:
CANADA RESEARCH CHAIRHOLDER / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA
  • 批准号:
    256327
  • 项目类别:
  • 资助金额:
    $36.43万
  • 财政年份:
    2011
  • 负责人:
    Sipione Simonetta
  • 依托单位:
海外基金