Therapeutic approach to preserve Tfh cells and improve B cell immunity in simian immunodeficiency virus infected rhesus macaques
Therapeutic approach to preserve Tfh cells and improve B cell immunity in simian immunodeficiency virus infected rhesus macaques
批准号:
434598
负责人:
Estaquier Jrôme
金额:
$81.37万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2020
资助国家:
加拿大
项目状态:
未结题
起止时间:
2020-10-01 至 2025-10-01
中文摘要
点击翻译按钮获取中文摘要
英文摘要
The depletion of CD4 T cells is a hallmark of HIV infection. A newly characterized population of CD4 T cells (T follicular helper, Tfh), which is essential for maintaining an efficient B cell immunity and for the maturation of HIV-specific antibodies, is
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Prevention of the immunopathology induced by SARS-CoV-2
-
批准号:448914
-
项目类别:Operating Grants
-
资助金额:$36.41万
-
财政年份:2021
-
负责人:Estaquier Jrôme
-
依托单位:
Canada Research Chair - Tier 1 - CIHR Funded
-
批准号:384869
-
项目类别:
-
资助金额:$101.99万
-
财政年份:2017
-
负责人:Estaquier Jrôme
-
依托单位:
Role of follicular CD8 T cells in the control of HIV/SIV mucosal immunity.
-
批准号:365664
-
项目类别:Operating Grants
-
资助金额:$18.21万
-
财政年份:2017
-
负责人:Estaquier Jrôme
-
依托单位:
Importance of tissue-resident memory (Trm) CD8 T cells in controlling SIV infection in mucosal sites of viral entry
-
批准号:323313
-
项目类别:Operating Grants
-
资助金额:$62.95万
-
财政年份:2015
-
负责人:Estaquier Jrôme
-
依托单位:
Analysis of T cell reservoirs in visceral tissues of pathogenic and non-pathogenic primate models of lentiviral SIV infection
-
批准号:292262
-
项目类别:Operating Grants
-
资助金额:$58.03万
-
财政年份:2013
-
负责人:Estaquier Jrôme
-
依托单位:
Analysis of infected CD4 T cell subsets in pathogenic and non-pathogenic primate models of lentiviral SIV infection
-
批准号:260351
-
项目类别:Operating Grants
-
资助金额:$7.29万
-
财政年份:2012
-
负责人:Estaquier Jrôme
-
依托单位:
Analysis of follicular helper T (Tfh) cells in pathogenic and non-pathogenic primate models of lentiviral SIV infection
-
批准号:275477
-
项目类别:Operating Grants
-
资助金额:$7.29万
-
财政年份:2012
-
负责人:Estaquier Jrôme
-
依托单位:
CANADA RESEARCH CHAIRHOLDER – TIER 1 / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA – NIVEAU 1
-
批准号:228298
-
项目类别:
-
资助金额:$101.99万
-
财政年份:2010
-
负责人:Estaquier Jrôme
-
依托单位:
海外基金