Live two-photon calcium imaging in retinal ganglion cells: characterization of pathological changes and mechanisms in glaucoma.

视网膜神经节细胞的实时双光子钙成像：青光眼病理变化和机制的表征。

• 批准号: 440681
• 负责人: Shiga Yukihiro
• 金额: $ 9.83万
• 依托单位: Centre hospitalier de l'Universit de Montral (CHUM)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=440681&lang=en
• 关键词: Glaucoma; In Vivo Imaging; Retinal Ganglion Cell

Glaucoma, characterized by the death of retinal ganglion cells (RGCs), is the leading cause of irreversible blindness worldwide. Glaucoma shares pathological features with a number of neurodegenerative conditions, most notably with Alzheimer's disease. On

以视网膜神经节细胞（RGC）死亡为特征的青光眼是全世界不可逆失明的主要原因。青光眼与许多神经退行性疾病有共同的病理特征，最显著的是与阿尔茨海默病。对