COVID-19 HALO open source ventilator

COVID-19 HALO 开源呼吸机

• 批准号: 550058-2020
• 负责人: Behdinan, Kamran
• 金额: $ 3.64万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Alliance Grants
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=701379
• 关键词: COVID; 19; HALO; open; source

The Covid-19 pandemic has led to health system crises around the globe. Patients with Covid-19 demonstrate oxygenation impairment and lung injury with severe cases requiring ventilatory support. The treatment of choice for patients who reach a critical state is positive pressure ventilation provided by standard critical care ventilators which are in limited supply. The manufacturers of these standard ventilators are unable to produce them in sufficient numbers for the surge in demand because of their complicated design and manufacturing. As a result, ventilator shortages have become a problem worldwide. In response, teams of engineers and physicians have developed high acuity, limited operability (HALO) ventilator systems whose designs allow for inexpensive and rapid manufacturing and are often under an open-source license. These devices provide automated positive pressure ventilatory support tailored to the specific needs of Covid-19-affected patients. These HALO designs use readily available off-the shelf components and are designed for easy manufacturing and rapid production. Unfortunately, many of these designs are in their early stages and have not undergone thorough clinical testing. Our project combines the expertise of physicians and engineers from the University of Toronto and Toronto General Hospital/University Health Network with individuals who have extensive experience in private medical device design, prototyping and manufacturing. This expertise will be used to create one prototype for testing, validation, and exploration of initial manufacturing partners to allow for rapid manufacturing of the validated design. These designs will be made available online under open-source GNU APLv3 and Creative Commons Share-alike licensing terms for local manufacturing in health systems around the world.

COVID-19大流行导致全球卫生系统危机。 COVID-19患者表现出氧合障碍和肺部损伤，严重病例需要通气支持。对于达到关键状态的患者的选择治疗是由标准重症监护剂提供的正压通风，该通风量有限。由于其复杂的设计和制造，这些标准呼吸机的制造商无法以足够数量的数量生产它们。结果，呼吸机短缺已成为全球问题。作为回应，工程师和医生团队已经开发出高敏锐度，有限的可操作性（Halo）呼吸机系统，其设计允许廉价且快速制造，并且经常受到开源许可。这些设备提供了针对COVID-19受影响患者的特定需求而定制的自动正压通气支持。这些光环设计使用容易获得的货架组件，设计用于易于制造和快速生产。不幸的是，其中许多设计处于早期阶段，并且没有进行彻底的临床测试。我们的项目结合了多伦多大学和多伦多大学综合医院/大学健康网络的医师和工程师的专业知识，并在私人医疗设备设计，原型制造和制造方面拥有丰富经验的个人。该专业知识将用于创建一个用于测试，验证和探索初始制造合作伙伴的原型，以允许快速制造经过验证的设计。这些设计将在全球卫生系统中的本地制造业的开源GNU APLV3和Creative Commons类似于股份的许可条款下在线提供。