COVID-19 HALO open source ventilator

COVID-19 HALO 开源呼吸机

• 批准号: 550058-2020
• 负责人: Behdinan, Kamran
• 金额: $ 3.64万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Alliance Grants
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=701379
• 关键词: COVID; 19; HALO; open; source

The Covid-19 pandemic has led to health system crises around the globe. Patients with Covid-19 demonstrate oxygenation impairment and lung injury with severe cases requiring ventilatory support. The treatment of choice for patients who reach a critical state is positive pressure ventilation provided by standard critical care ventilators which are in limited supply. The manufacturers of these standard ventilators are unable to produce them in sufficient numbers for the surge in demand because of their complicated design and manufacturing. As a result, ventilator shortages have become a problem worldwide. In response, teams of engineers and physicians have developed high acuity, limited operability (HALO) ventilator systems whose designs allow for inexpensive and rapid manufacturing and are often under an open-source license. These devices provide automated positive pressure ventilatory support tailored to the specific needs of Covid-19-affected patients. These HALO designs use readily available off-the shelf components and are designed for easy manufacturing and rapid production. Unfortunately, many of these designs are in their early stages and have not undergone thorough clinical testing. Our project combines the expertise of physicians and engineers from the University of Toronto and Toronto General Hospital/University Health Network with individuals who have extensive experience in private medical device design, prototyping and manufacturing. This expertise will be used to create one prototype for testing, validation, and exploration of initial manufacturing partners to allow for rapid manufacturing of the validated design. These designs will be made available online under open-source GNU APLv3 and Creative Commons Share-alike licensing terms for local manufacturing in health systems around the world.

新冠肺炎疫情已导致全球卫生系统危机。新冠肺炎的患者表现为氧合障碍和肺损伤，严重者需要呼吸机支持。对于达到危重状态的患者，首选的治疗方法是由有限供应的标准危重呼吸机提供的正压呼吸机。由于其复杂的设计和制造，这些标准通风机的制造商无法生产足够数量的通风机来满足激增的需求。因此，呼吸机短缺已成为全球范围内的一个问题。作为回应，工程师和医生团队开发了高敏锐度、有限可操作性(Halo)呼吸机系统，其设计允许廉价和快速制造，并且通常是在开源许可下进行的。这些设备提供根据新冠肺炎患者的特定需求量身定做的自动化正压呼吸机支持。这些Halo设计使用现成的组件，易于制造和快速生产。不幸的是，这些设计中的许多还处于早期阶段，没有经过彻底的临床测试。我们的项目结合了来自多伦多大学和多伦多综合医院/大学健康网络的医生和工程师的专业知识，以及在私人医疗设备设计、原型和制造方面拥有丰富经验的个人。这些专业知识将被用来创建一个原型，用于测试、验证和探索初始制造合作伙伴，以允许快速制造经过验证的设计。这些设计将在开源GNU APLv3和Creative Commons Share相似的许可条款下在线提供，用于世界各地卫生系统的本地制造。