COVID-19 HALO open source ventilator

2019冠状病毒病大流行导致全球卫生系统出现危机。Covid-19患者表现为氧合功能障碍和肺损伤，严重者需要呼吸机支持。达到危重状态的患者的治疗选择是由供应有限的标准重症监护呼吸机提供正压通气。这些标准呼吸机的制造商由于其复杂的设计和制造，无法生产足够数量的产品来满足激增的需求。因此，呼吸机短缺已成为一个世界性的问题。作为回应，工程师和医生团队开发了高灵敏度、有限可操作性（HALO）呼吸机系统，其设计允许廉价和快速的制造，并且通常是在开源许可下。这些设备可根据受covid -19影响患者的特定需求提供自动正压通气支持。这些HALO设计使用现成的现成组件，设计用于易于制造和快速生产。不幸的是，这些设计中有许多还处于早期阶段，没有经过彻底的临床试验。我们的项目结合了多伦多大学和多伦多总医院/大学健康网络的医生和工程师的专业知识，以及在私人医疗设备设计，原型制作和制造方面拥有丰富经验的个人。该专业知识将用于创建一个原型，用于测试、验证和探索初始制造合作伙伴，以允许验证设计的快速制造。这些设计将在开放源代码的GNU APLv3和知识共享类似许可条款下在线提供，用于世界各地卫生系统的本地制造。

The Covid-19 pandemic has led to health system crises around the globe. Patients with Covid-19 demonstrate oxygenation impairment and lung injury with severe cases requiring ventilatory support. The treatment of choice for patients who reach a critical state is positive pressure ventilation provided by standard critical care ventilators which are in limited supply. The manufacturers of these standard ventilators are unable to produce them in sufficient numbers for the surge in demand because of their complicated design and manufacturing. As a result, ventilator shortages have become a problem worldwide. In response, teams of engineers and physicians have developed high acuity, limited operability (HALO) ventilator systems whose designs allow for inexpensive and rapid manufacturing and are often under an open-source license. These devices provide automated positive pressure ventilatory support tailored to the specific needs of Covid-19-affected patients. These HALO designs use readily available off-the shelf components and are designed for easy manufacturing and rapid production. Unfortunately, many of these designs are in their early stages and have not undergone thorough clinical testing. Our project combines the expertise of physicians and engineers from the University of Toronto and Toronto General Hospital/University Health Network with individuals who have extensive experience in private medical device design, prototyping and manufacturing. This expertise will be used to create one prototype for testing, validation, and exploration of initial manufacturing partners to allow for rapid manufacturing of the validated design. These designs will be made available online under open-source GNU APLv3 and Creative Commons Share-alike licensing terms for local manufacturing in health systems around the world.