How ROS modulate the oncogenic Ras signaling pathway to promote longevity

ROS 如何调节致癌 Ras 信号通路以延长寿命

• 批准号: 449498
• 负责人: Chang Maggie
• 金额: $ 1.27万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-12-01 至 2021-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=449498&lang=en
• 关键词: Aging; C. Elegans; Ras Signaling; Reactive Oxygen Species; Ros Signaling

For decades, antioxidants have been believed to be a key to anti-aging. Yet, several studies have shown that reactive oxygen species (ROS), which are antagonized by antioxidants, may in fact help combat aging. In roundworms, lifespan can be increased by t

几十年来，人们认为抗氧化剂是抗衰老的关键。然而，一些研究表明，被抗氧化剂拮抗的活性氧（ROS）实际上可能有助于对抗衰老。在round虫中，寿命可以通过t增加