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Apoptosis and early stage atherosclerosis: studies aimed at defining and regulating the mechanism by which cellular inhibitor of apoptosis protein 2 (cIAP2) contributes to early lesion formation

Apoptosis and early stage atherosclerosis: studies aimed at defining and regulating the mechanism by which cellular inhibitor of apoptosis protein 2 (cIAP2) contributes to early lesion formation
细胞凋亡和早期动脉粥样硬化：旨在定义和调节细胞凋亡蛋白抑制剂 2 (cIAP2) 促进早期病变形成的机制的研究
批准号：
179365
负责人：
Whitman Stewart C
金额：
$7.29万
依托单位：
University of Ottawa Heart Institute
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2008
资助国家：
加拿大
项目状态：
已结题
起止时间：
2008-09-01 至 2009-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=179365&lang=en
关键词：
Apoptosis Atherosclerosis Bone Marrow Transplantation Macrophage Mouse Models Of Disease

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Objective: Under different circumstances both anti- and pro-apoptotic mechanisms contribute to the development and progression of atherosclerosis, yet the molecular events leading to these processes are not clearly understood. Macrophages are a key compo
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