Microbial-Derived D-lactate Modulates Inflammation and Contributes to Insulin Resistance
Microbial-Derived D-lactate Modulates Inflammation and Contributes to Insulin Resistance
批准号:
449808
负责人:
Singh Anita
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2020
资助国家:
加拿大
项目状态:
已结题
起止时间:
2020-12-01 至 2021-12-01
中文摘要
肥胖引起的炎症会促进2型糖尿病和非酒精性脂肪肝,这些疾病与肠道微生物组的变化有关。最近的证据表明,肠道微生物群通过肝细胞调节血糖稳态。
英文摘要
Obesity-induced inflammation promotes type 2 diabetes and non-alcoholic fatty liver disease, which are associated with changes in the intestinal microbiome. Recent evidence showed that gut microbiota regulate blood glucose homeostasis via hepatic gluconeo
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