Dysregulating the mitochondrial caseinolytic protease P (hClpP) for combating acute myeloid leukaemia

线粒体酪蛋白分解酶 P (hClpP) 失调可对抗急性髓系白血病

• 批准号: 449801
• 负责人: Sever Alexander I
• 金额: $ 1.27万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-12-01 至 2021-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=449801&lang=en
• 关键词: Acute Myeloid Leukaemia; Dynamics; Electron Cryo-Microscopy; Mitochondrial Caseinolytic Protease P; Nuclear Magnetic Resonance

Proteins are large biological molecules that perform many of the critical functions in cells. Often these proteins are organized as molecular machines and, like their macroscopic counterparts, these machines work through a series of moving parts. Only thr

蛋白质是在细胞中执行许多关键功能的大型生物分子。通常，这些蛋白质被组织成分子机器，就像它们的宏观对应物一样，这些机器通过一系列活动部件工作。只有用力推