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Regenerating Human Pancreatic Beta Cells to Treat Diabetes

Regenerating Human Pancreatic Beta Cells to Treat Diabetes
再生人胰腺β细胞治疗糖尿病
批准号：
446712
负责人：
Screaton Robert A
金额：
$0.73万
依托单位：
Sunnybrook Research Institute (Toronto, Ontario)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2020
资助国家：
加拿大
项目状态：
已结题
起止时间：
2020-12-01 至 2021-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=446712&lang=en
关键词：
Animal Models Beta Cells Cell Cycle Crispr Diabetes G Protein Coupled Receptors Human Es Cells Incretins Islets Rnai

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中文摘要
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英文摘要
Our vision is to establish a complete understanding of the biology of human beta cells, the cells that make and secrete insulin after a meal. The inability to produce enough insulin results in diabetes mellitus (DM), and affects over 13M Canadians. While
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Role of the GPR3-SIK2 Pathway in Human Beta Cell Proliferation
Role of the GPR3-SIK2 Pathway in Human Beta Cell Proliferation
Establishing a Comprehensive Genetic Roadmap for Human Pancreatic Beta Cell Proliferation and Function
Novel Regulators of Mitochondrial Dynamics
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