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Role of the GPR3-SIK2 Pathway in Human Beta Cell Proliferation

Role of the GPR3-SIK2 Pathway in Human Beta Cell Proliferation
GPR3-SIK2 通路在人 β 细胞增殖中的作用
批准号:
462043
负责人:
Screaton Robert A
金额:
$62.98万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-03-01 至 2027-03-01

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英文摘要
Our vision is to establish a complete understanding of the biology of human beta cells, the cells that make and secrete insulin after a meal. The inability to produce enough insulin results in diabetes mellitus (DM), and affects over 13M Canadians. While
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Role of the GPR3-SIK2 Pathway in Human Beta Cell Proliferation
Regenerating Human Pancreatic Beta Cells to Treat Diabetes
Establishing a Comprehensive Genetic Roadmap for Human Pancreatic Beta Cell Proliferation and Function
Novel Regulators of Mitochondrial Dynamics
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