Effects of Age-Related Macrophage Dysfunctions on Atherosclerosis Regression

年龄相关的巨噬细胞功能障碍对动脉粥样硬化消退的影响

• 批准号: 449386
• 负责人: Boucher Dominique M
• 金额: $ 1.27万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-12-01 至 2021-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=449386&lang=en
• 关键词: Aging; Atherosclerosis; Foam Cells; Macrophage; Regression; Senescence

Atherosclerosis is a disease characterised by the build-up of plaque in blood vessels. These plaques, comprised of cholesterol, fibrous material, and cells of muscle and immune origin, arise in conditions of high blood cholesterol, where cholesterol can d

动脉粥样硬化是一种以斑块在血管中积聚为特征的疾病。这些斑块由胆固醇、纤维物质、肌肉细胞和免疫源性细胞组成，在高血胆固醇的情况下出现，胆固醇可以通过免疫途径降解。