Chronic stress induces increased blood-brain barrier transcytosis and passage of circulating proinflammatory mediators into the brain contributing to the pathogenesis of depression
Chronic stress induces increased blood-brain barrier transcytosis and passage of circulating proinflammatory mediators into the brain contributing to the pathogenesis of depression
批准号:
441336
负责人:
Neutzling Kaufmann Fernanda
金额:
$9.83万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2020
资助国家:
加拿大
项目状态:
已结题
起止时间:
2020-12-01 至 2023-12-01
中文摘要
重度抑郁症(MDD)影响着全世界3.22亿人。慢性应激是导致抑郁症的主要环境危险因素,可促进免疫系统失调和免疫细胞的募集以及有害的炎症介质,
英文摘要
Major depressive disorder (MDD) affects 322 million people around the world. Chronic stress, the main environmental risk factor leading to depression, can promote immune system dysregulation and recruitment of immune cells and deleterious inflammatory med
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