Mass spec studio: business intelligence software for the international laboratory industry (a Phase IIb project)

Mass spec studio：国际实验室行业的商业智能软件（IIb 期项目）

• 批准号: 557341-2020
• 负责人: Schriemer, David
• 金额: $ 10.6万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Idea to Innovation
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=706559
• 关键词: Mass; spec; studio; business; intelligence

Many chronic human conditions remain poorly treated. Diseases like cancer, arthritis, gastrointestinal disorders, kidney disease and many others lack effective therapies. It is the goal of modern medicine to develop drugs for these diseases and improve the health-span of society. The effort involves fundamental research into the nature of disease, drug product discovery and development, and drug monitoring. All these activities stretch over multiple industries and rely heavily upon scientific tools of molecular analysis, like the mass spectrometer. These tools are used to discover drugs, shorten the path to their development, ensure product safety and determine if the drugs are working in the population. Mass spectrometers, like many modern tools of analysis, generate complex data streams that are difficult to interpret. The current project will launch a powerful development framework called the Mass Spec Studio to create software products for data analytics. This proprietary framework is an app development generator that supports mass spectrometry and can be expanded to other techniques. The project will deliver its flagship product (HXauto) for measuring the safety and stability of biologics, an important new class of drug therapy. Successful commercialization of HXauto will validate our business plans and lead to a new Canadian software design firm in partnership with a major international life sciences company.

许多慢性人类疾病仍然没有得到很好的治疗。像癌症、关节炎、胃肠道疾病、肾脏疾病和许多其他疾病缺乏有效的治疗方法。现代医学的目标是开发治疗这些疾病的药物，提高社会的健康寿命。这项工作涉及对疾病性质的基础研究，药物产品的发现和开发以及药物监测。所有这些活动都涉及多个行业，并严重依赖分子分析的科学工具，如质谱仪。这些工具用于发现药物，缩短其开发路径，确保产品安全性并确定药物是否在人群中起作用。质谱仪与许多现代分析工具一样，会产生难以解释的复杂数据流。目前的项目将推出一个名为Mass Spec Studio的强大开发框架，以创建数据分析软件产品。这个专有框架是一个应用程序开发生成器，支持质谱分析，并可以扩展到其他技术。该项目将提供其旗舰产品（HXauto），用于测量生物制剂的安全性和稳定性，这是一类重要的新型药物治疗。HXauto的成功商业化将验证我们的商业计划，并导致一个新的加拿大软件设计公司与一个主要的国际生命科学公司合作。