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Development of Molecular Imaging Tools to Monitor the Fate of an Off-The-Shelf Chimeric Antigen Receptor Natural Killer (CAR-NK) Cell Immunotherapy

Development of Molecular Imaging Tools to Monitor the Fate of an Off-The-Shelf Chimeric Antigen Receptor Natural Killer (CAR-NK) Cell Immunotherapy
开发分子成像工具来监测现成的嵌合抗原受体自然杀伤 (CAR-NK) 细胞免疫疗法的命运
批准号：
444870
负责人：
Ronald John A
金额：
$58.24万
依托单位：
University of Western Ontario
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2021
资助国家：
加拿大
项目状态：
未结题
起止时间：
2021-04-01 至 2026-04-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=444870&lang=en
关键词：
Cancer Immunotherapy Chimeric Antigen Receptor Human Epidermal Receptor-2 (Her2) Magnetic Resonance Imaging Molecular Imaging Natural Killer Cells Ovarian Cancer Positron Emission Tomography Reporter Gene

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中文摘要
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英文摘要
Chimeric antigen receptor natural killer (CAR-NK) cell therapy involves modifying NK cells to in the lab with a CAR to redirect them to interact with and kill cancer cells once infused into a cancer patient. This therapy has shown tremendous potential as
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Development of Molecular Imaging Tools to Monitor the Fate of an Off-The-Shelf Chimeric Antigen Receptor Natural Killer (CAR-NK) Cell Immunotherapy for Breast Cancer
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    443058
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    Operating Grants
  • 资助金额：
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    2020
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    University of Western Ontario
Blood-based detection and molecular imaging visualization of cancer using reporter gene vectors called tumor-activatable minicircles
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    356944
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Multi-modality cell trafficking imaging using optical bioluminescent imaging, positron emission tomography (PET) and magnetic resonance imaging (MRI)
  • 批准号：
    181317
  • 项目类别：
    Fellowship Programs
  • 资助金额：
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  • 财政年份：
    2009
  • 负责人：
    Ronald John A
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