Prospective, multicentre, randomized, parallel-control, superiority study comparing administration of clotting factor concentrates with a standard massive hemorrhage protocol in severely bleeding trauma patients

前瞻性、多中心、随机、平行对照、优效性研究，对严重出血创伤患者使用凝血因子浓缩物与标准大出血方案进行比较

• 批准号: 444024
• 负责人: Callum Jeannie L
• 金额: $ 74.4万
• 依托单位: University Health Network (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-04-01 至 2024-04-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=444024&lang=en
• 关键词: Bleeding; Coagulopathy; Haemorrhage; Hypofibrinogenemia; Inury; Trauma

When a patient is severely injured (e.g., high speed car crash, or a pedestrian struck by a car) the most common cause of death is uncontrollable bleeding. The bleeding results from both injury to major blood vessels and from loss of clotting factors in t

当病人受重伤时(例如，高速车祸或行人被车撞)，最常见的死亡原因是失控出血。出血既是主要血管损伤的结果，也是凝血因子丢失的结果。