Rational design of new drug candidates for the treatment of Trypanosoma cruzi infection

治疗克氏锥虫感染候选新药的合理设计

• 批准号: LP110100306
• 负责人: Prof Susan Charman
• 金额: $ 41.64万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-05-18 至 2014-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP110100306
• 关键词: Rational; design; new; drug; candidates

There is a serious shortage of safe and effective drugs to treat Chagas disease which is caused by a parasitic infection. This project aims to design and identify new drug candidates by defining the disposition profile within the body which is necessary to achieve a therapeutic effect.

治疗由寄生虫感染引起的恰加斯病的安全有效药物严重短缺。该项目旨在通过定义实现治疗效果所需的体内分布特征来设计和识别新的候选药物。