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Influence of Ikaros on treatment response in Acute Lymphoblastic Leukemia

Influence of Ikaros on treatment response in Acute Lymphoblastic Leukemia
Ikaros 对急性淋巴细胞白血病治疗反应的影响
批准号:
452692
负责人:
Milot Eric
金额:
$63.25万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-09-01 至 2026-09-01

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中文摘要
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英文摘要
The transcription factor Ikaros is frequently disrupted in acute lymphoblastic leukemia (ALL) and chronic myeloid leukemia (CML) at the blast crisis phase. Such is associated with poor clinical outcome. The precise molecular functions of Ikaros are unclea
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Ikaros regulation of transcription elongation and its importance during hematopoiesis
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