A novel regulator of prefrontal circuit function in affective behaviour

情感行为中前额叶回路功能的新型调节器

• 批准号: 451392
• 负责人: Bagot Rosemary C
• 金额: $ 79.42万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-09-01 至 2026-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=451392&lang=en
• 关键词: Chronic Stress; In Vitro Electrophysiology; Plasticity; Prefrontal Cortex; Reward; Rnascope; Sdk1; Single Cell Rna-Seq; Social Interaction

Depression and other mood disorders involve changes in emotional brain circuits. Recent advances make it possible to begin to probe molecular mechanisms of circuit changes. In this search we have identified a novel gene that may influence depression risk

抑郁症和其他情绪障碍涉及情绪大脑回路的变化。最近的进展使得开始探测电路变化的分子机制成为可能。在这项研究中，我们发现了一种可能影响抑郁风险的新基因。