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Preclinical safety, pharmacokinetics, pharmacodynamics, and efficiency of microRNA oligonucleotides for Alzheimer's disease

Preclinical safety, pharmacokinetics, pharmacodynamics, and efficiency of microRNA oligonucleotides for Alzheimer's disease
microRNA寡核苷酸治疗阿尔茨海默病的临床前安全性、药代动力学、药效学和功效
批准号:
450756
负责人:
Hbert Sbastien
金额:
$83.79万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-09-01 至 2026-09-01

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中文摘要
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英文摘要
Alzheimer's disease is the most prevalent neurodegenerative disease and the most common cause of dementia. It affects not only the people living with the disease but also theirs families and surroundings. Unfortunately, there is no cure or treatment for A
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Preclinical safety, pharmacokinetics, pharmacodynamics, and efficiency of microRNA oligonucleotides for Alzheimer's disease
  • 批准号:
    414963
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2019
  • 负责人:
    Hbert Sbastien
  • 依托单位:
microRNA-132: from underlying mechanism of neurodegeneration to therapeutic application in Huntington's disease
  • 批准号:
    355498
  • 项目类别:
    Operating Grants
  • 资助金额:
    $41.8万
  • 财政年份:
    2016
  • 负责人:
    Hbert Sbastien
  • 依托单位:
GWAS in AD: focus on microRNA
  • 批准号:
    337222
  • 项目类别:
    Operating Grants
  • 资助金额:
    $22.95万
  • 财政年份:
    2015
  • 负责人:
    Hbert Sbastien
  • 依托单位:
MicroRNA-15 dysregulation in sporadic Alzheimer's disease: testing the "multiple hit" hypothesis in neurodegenerative disorders
  • 批准号:
    252184
  • 项目类别:
    Operating Grants
  • 资助金额:
    $42.34万
  • 财政年份:
    2012
  • 负责人:
    Hbert Sbastien
  • 依托单位:
海外基金