Identification of the immunologic mechanisms leading to flares of disease activity in Systemic Lupus Erythematosus
Identification of the immunologic mechanisms leading to flares of disease activity in Systemic Lupus Erythematosus
批准号:
451691
负责人:
Wither Joan E
金额:
$50.44万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-09-01 至 2026-09-01
中文摘要
点击翻译按钮获取中文摘要
英文摘要
In lupus, antibodies are mistakenly produced against molecules that are part of the body, such as DNA and other proteins found in the nuclei of cells (ANAs), which then deposit in the organs causing inflammation and damage. Lupus follows an unpredictable
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Characterization of the T cell populations that regulate autoimmunity in asymptomatic anti-nuclear positive individuals and how they become altered in early untreated systemic autoimmune rheumatic disease
-
批准号:490019
-
项目类别:Operating Grants
-
资助金额:$66.32万
-
财政年份:2023
-
负责人:Wither Joan E
-
依托单位:
Characterization of the immunologic events that lead to development of Systemic Autoimmune Rheumatic Disease
-
批准号:380262
-
项目类别:Operating Grants
-
资助金额:$58.58万
-
财政年份:2018
-
负责人:Wither Joan E
-
依托单位:
Development of a test for the early diagnosis and monitoring of lupus nephritis
-
批准号:335162
-
项目类别:Operating Grants
-
资助金额:$11.66万
-
财政年份:2015
-
负责人:Wither Joan E
-
依托单位:
Cellular and molecular characterization of lupus susceptibility genes using congenic mouse strains
-
批准号:191257
-
项目类别:Operating Grants
-
资助金额:$53.88万
-
财政年份:2009
-
负责人:Wither Joan E
-
依托单位:
Characterization of intrinsic B cell defects and their role in the immunopathogenesis of murine lupus
-
批准号:191331
-
项目类别:Operating Grants
-
资助金额:$52.49万
-
财政年份:2009
-
负责人:Wither Joan E
-
依托单位:
Characterization of B cell tolerance and functional abnormalities in human lupus
-
批准号:170482
-
项目类别:Operating Grants
-
资助金额:$26.5万
-
财政年份:2008
-
负责人:Wither Joan E
-
依托单位:
国内基金
海外基金
长效GnRHa“flare-up”效应通过AMPK通路抑制子宫腺肌症患者卵泡发育的机制
-
批准号:81801418
-
项目类别:青年科学基金项目
-
资助金额:21.0万元
-
批准年份:2018
-
负责人:陆小溦
-
依托单位: