Humanization of skeletal muscle innervation to study ALS
Humanization of skeletal muscle innervation to study ALS
批准号:
450942
负责人:
Rafuse Victor F
金额:
$65.76万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-09-01 至 2026-09-01
中文摘要
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英文摘要
ALS is a motoneuron neurodegenerative disease that predominantly effects elderly people. Most in vivo and in vitro studies
studying ALS either use models that die early in life or use tissue culture (i.e. human induced pluripotent stem cell-derived
motone
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会议论文
Deciphering the mechanisms underlying synaptic dysfunction at the neuromuscular junction in Amyotrophic Lateral Sclerosis (ALS)
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批准号:344599
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项目类别:Operating Grants
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资助金额:$49.29万
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财政年份:2016
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负责人:Rafuse Victor F
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依托单位:
Restoring useful function to complete and permanently denervated skeletal muscles
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批准号:342891
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项目类别:Operating Grants
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资助金额:$52.63万
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财政年份:2016
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负责人:Rafuse Victor F
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依托单位:
Optical control of dysfunctional muscles
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批准号:332999
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项目类别:Operating Grants
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资助金额:$7.29万
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财政年份:2015
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负责人:Rafuse Victor F
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依托单位:
Developing specific motoneuron subtypes from embryonic stem cells, and induced pluripotent stem cells, to treat neuromuscular disorders and paralysis due to injury.
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批准号:205851
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项目类别:Operating Grants
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资助金额:$28.57万
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财政年份:2010
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负责人:Rafuse Victor F
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依托单位:
海外基金