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A Phase I first-in-human trial of CLIC-2201, a VHH-CD22 CAR-T cell product for the treatment of relapsed/refractory CD22 positive B-cell non-Hodgkin lymphoma

A Phase I first-in-human trial of CLIC-2201, a VHH-CD22 CAR-T cell product for the treatment of relapsed/refractory CD22 positive B-cell non-Hodgkin lymphoma
CLIC-2201 的 I 期首次人体试验,CLIC-2201 是一种 VHH-CD22 CAR-T 细胞产品,用于治疗复发/难治性 CD22 阳性 B 细胞非霍奇金淋巴瘤
批准号:
453064
负责人:
Hay Kevin A
金额:
$121.49万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-09-01 至 2025-09-01

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中文摘要
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英文摘要
Chimeric antigen receptor (CAR)-T cell therapy targeting CD19, a marker on B cell cancers, is a novel approach that has induced meaningful and durable remissions for many patients and is now considered standard of care therapy in relapsed disease. This th
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A Phase I trial of single domain antibody-based CD22 chimeric antigen receptor (CAR)-T cells for the treatment of relapsed/refractory CD22+ B-cell acute lymphoblastic leukemia
  • 批准号:
    466359
  • 项目类别:
    Operating Grants
  • 资助金额:
    $222.3万
  • 财政年份:
    2022
  • 负责人:
    Hay Kevin A
  • 依托单位:
A Phase I trial of single domain antibody-based CD22 chimeric antigen receptor (CAR)-T cells for the treatment of relapsed/refractory CD22+ B-cell acute lymphoblastic leukemia
  • 批准号:
    474613
  • 项目类别:
    Operating Grants
  • 资助金额:
    $55.58万
  • 财政年份:
    2022
  • 负责人:
    Hay Kevin A
  • 依托单位:
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