The role of titin elasticity in cardiomyopathy

肌动蛋白弹性在心肌病中的作用

• 批准号: 454925
• 负责人: Xia Jiahao
• 金额: $ 9.83万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-10-01 至 2024-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=454925&lang=en
• 关键词: Cardiomyopathy; Protein Biophysics; Single Molecule Force Spectroscopy; Titin

Cardiomyopathy, a major contributor to heart failure, is a heart muscle disease that reduces the heart's ability to pump blood. The elastic properties of the cardiac muscle protein titin are thought to be closely associated with this disease. Previous stu

心肌病是导致心力衰竭的主要因素，是一种降低心脏泵血能力的心肌疾病。心肌蛋白质Titin的弹性特性被认为与这种疾病密切相关。 上一篇文章