NSERC Medtronic Industrial Research Chair in Spine Biomechanics / Chaire de recherche industrielle CRSNG Medtronic en biomécanique de la colonne vertébrale

NSERC 美敦力脊柱生物力学工业研究主席 / Chaire de recherche industrielle CRSNG 美敦力脊椎生物力学

• 批准号: 346145-2016
• 负责人: Aubin, CarlEric
• 金额: $ 12.75万
• 依托单位: École Polytechnique de Montréal
• 依托单位国家: 加拿大
• 项目类别: Industrial Research Chairs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=719006
• 关键词: NSERC; Medtronic; Industrial; Research; Chair

Biomedical engineering and medical technology (medtech) industry in the field of spine orthopedics facesincreasing challenges to develop high-quality engineering solutions to treat spine pathologies as well as rapidlyimplement research findings to the users. The spine is a complex and central component of our body, involvedin posture equilibrium, movements, and protection of the spinal cord. Severe spinal deformities, trauma, anddegenerative conditions are generally treated with spinal instrumentation surgery involving fusion. This is anextensive and invasive procedure that permanently restricts motion of spinal segments and places additionalstress on the junction between fused and unfused segments and within the construct, especially at thebone-implant interface and in dense constructs. Despite significant improvements in biomedical technologiesover the last decades, spinal surgeries remain very invasive while techniques continue to be mostly empiricaland surgeon-specific. This is an area where engineering research is crucial to improve knowledge of spinebiomechanics.The research program aims to develop and apply biomechanical engineering methods to: 1) Improveunderstanding of the 3 dimensional spine biomechanics to explore new devices, post-surgical conditions and,concurrently, develop instrumentation guidelines. 2) Develop validated simulation tools aimed at analyzing andimproving instrumentation technologies and surgical strategies; 3) Develop and validate innovative tools forsurgical planning, intra-operative guidance, and post-op management of spinal pathologies. In summary, thescientific and technological achievements of the Chair will represent major assets in the global competitionnow underway to master advanced knowledge of spine biomechanics and related technologies, and developcomprehensive engineering tools to address important needs from the spine orthopedic medtech industry,resulting in less invasive and optimal surgeries with all the expected economic benefits to the Canadianbiomedical industry, patients, and society.

脊柱骨科领域的生物医学工程和医疗技术 (medtech) 行业面临着越来越多的挑战，需要开发高质量的工程解决方案来治疗脊柱病理，并快速向用户实施研究成果。脊柱是我们身体的一个复杂的核心组成部分，参与姿势平衡、运动和脊髓的保护。严重的脊柱畸形、创伤和退行性疾病通常通过涉及融合的脊柱内固定手术来治疗。这是一种广泛的侵入性手术，永久限制脊柱节段的运动，并对融合节段和未融合节段之间以及结构内的连接处施加额外的应力，特别是在骨植入物界面和致密结构中。尽管过去几十年生物医学技术取得了显着进步，但脊柱手术仍然具有很强的侵入性，而技术仍然主要是经验性的和外科医生特定的。这是一个工程研究对于提高脊柱生物力学知识至关重要的领域。该研究项目旨在开发和应用生物力学工程方法来：1）提高对 3 维脊柱生物力学的理解，以探索新设备、术后条件，同时制定仪器指南。 2）开发经过验证的模拟工具，旨在分析和改进仪器技术和手术策略； 3) 开发并验证脊柱病理的手术计划、术中指导和术后管理的创新工具。总之，主席的科学技术成就将代表目前正在进行的全球竞争的主要资产，以掌握脊柱生物力学和相关技术的先进知识，并开发综合工程工具来满足脊柱骨科医疗技术行业的重要需求，从而实现微创和最佳手术，为加拿大生物医学行业、患者和社会带来所有预期的经济效益。