Neurovascular biology underlying protective effects of enriched environment and physical exercise in the context of chronic stress

神经血管生物学揭示了慢性应激背景下丰富环境和体育锻炼的保护作用

• 批准号: 467125
• 负责人: Paton Sam E
• 金额: $ 1.27万
• 依托单位: Universit Laval
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-12-01 至 2022-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=467125&lang=en
• 关键词: Blood Brain Barrier; Depression; Inflammation; Preventative Strategies; Sex Differences; Stress; Tight Junction

Major depressive disorder (MDD) is a leading cause of disability worldwide, including 11% of men and 16% of women in Canada. Still, nearly half of all MDD patients are unresponsive to currently available antidepressants. This suggests that there are under

重度抑郁症（MDD）是全球残疾的主要原因，在加拿大，11%的男性和16%的女性患有MDD。尽管如此，近一半的MDD患者对目前可用的抗抑郁药无反应。这表明，