Defining ER stress profiles as determinants of cell identity and therapeutic vulnerability in mTORC1-driven brain tumours

将 ER 应激谱定义为 mTORC1 驱动的脑肿瘤细胞身份和治疗脆弱性的决定因素

• 批准号: 468026
• 负责人: Julian Lisa M
• 金额: $ 4.37万
• 依托单位: Simon Fraser University (Burnaby, B.C.)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-02-01 至 2024-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=468026&lang=en
• 关键词: Brain And Nervous System; Childhood And Young Adult; Genetic Causes Of Cancer; Imaging Technologies; Multiple Cancers

As we seek to develop more effective treatment strategies for cancer it's essential to better understand the biological processes that are initially responsible for giving rise to tumours. This can reveal which processes are fundamental to the function of

当我们寻求开发更有效的癌症治疗策略时，有必要更好地了解最初导致肿瘤产生的生物过程。这可以揭示哪些过程是功能的基础