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Reprogramming Patient-Derived Induced Pluripotent Stem Cells to Model Lymphangioleiomyomatosis (LAM) and Identify Novel Therapeutic Targets

Reprogramming Patient-Derived Induced Pluripotent Stem Cells to Model Lymphangioleiomyomatosis (LAM) and Identify Novel Therapeutic Targets
重新编程患者来源的诱导多能干细胞来模拟淋巴管平滑肌瘤病 (LAM) 并确定新的治疗靶点
批准号：
296990
负责人：
Julian Lisa M
金额：
$10.2万
依托单位：
Ottawa Hospital Research Institute
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-10-01 至 2015-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=296990&lang=en
关键词：
Cancer Biology Disease Modeling Identification Of Therapeutic Targets Induced Pluripotent Stem Cells Lymphangioleiomyomatosis Neural Crest Stem Cells Personalized Medicine Stem Cell Fate Decisions Systems Biology Tuberous Sclerosis Complex

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Lymphangioleiomyomatosis is a devastating form of cancer, characterized by the abnormal growth of cells resembling smooth muscle cells in the lungs of affected patients. This disease primarily affects young to middle aged women, and causes lung tissue des
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