Chemistry Of Biological Nano-Assemblies

生物纳米组件的化学

• 批准号: CRC-2016-00033
• 负责人: Bourgault, Steve
• 金额: $ 8.74万
• 依托单位: Université du Québec à Montréal
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=729706
• 关键词: Chemistry; Biological; Nano; Assemblies

Living organisms are an inestimable source of inspiration for the design of nanomaterials for medical and technological applications. Amyloid fibrils have been recently recognized as promising biomaterials with unique chemical and mechanical properties. These organized nanostructures are formed by the spontaneous self-assembly of a large diversity of proteins. The overarching goal of the proposed Canada Research Chair in Chemistry of Biological Nano-Assemblies is to heighten the fundamental study of amyloid formation in order to control and manipulate self-recognition. We will take advantage of this knowledge to design functionalized protein materials and biomatrices for innovative applications in nanomedicine and biotechnology.

生物体是设计用于医疗和技术应用的纳米材料的不可估量的灵感来源。淀粉样原纤维具有独特的化学和力学性质，是一种很有前途的生物材料。这些有组织的纳米结构是由多种蛋白质自发自组装形成的。拟议的加拿大生物纳米组装化学研究主席的总体目标是加强淀粉样蛋白形成的基础研究，以控制和操纵自我识别。我们将利用这些知识来设计功能化蛋白质材料和生物基质，用于纳米医学和生物技术的创新应用。