Neurogenomics

DNA编码生物体中的遗传信息，为了确保这种材料正确地传递遗传数据，对DNA发生的损伤进行准确修复至关重要。由于大脑消耗大量的能量，组织中的细胞暴露在大量的损伤中，这些损伤通过复杂的生物途径得到修复。赖特博士的研究计划将使用先进的计算方法来研究高通量基因组数据，以揭示涉及大脑DNA损伤反应和修复的基因和途径的新机制见解。

DNA encodes hereditary information in living organisms ¿ in order to ensure that this material conveys genetic data correctly, it is essential that damage that occurs to DNA is accurately repaired. Since the brain consumes large amounts of energy, the cells in this tissue are exposed to a substantial amount of damage, which is repaired via complex biological pathways. Dr. Wright¿s research program will use advanced computational approaches to study high throughput genomic data to uncover novel mechanistic insights into the genes and pathways involved in DNA damage response and repair in the brain.