Chemistry

化学

• 批准号: CRC-2019-00425
• 负责人: Hedberg, Yolanda
• 金额: $ 8.74万
• 依托单位: University of Western Ontario
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=730836
• 关键词: Chemistry

Medical implants, drinking water quality, and the metallic smell in the subway are all influenced by the interface between metals and biomolecules. This interface never sleeps: physical, chemical, and electrochemical reactions are constantly ongoing and influence each other. This research program aims to increase the safety of biomedical materials and their use by predicting reaction mechanisms and rates at metal-bio interfaces, such as for metallic implant materials and metal nanoparticles used for nanomedical applications. The corrosion mechanisms of these metal devices, dependent on their composition, design, manufacture, and the patient¿s infection status, must be understood for optimal application.

医疗植入物、饮用水质量和地铁中的金属气味都受到金属和生物分子之间界面的影响。这个界面从不睡觉：物理，化学和电化学反应不断进行并相互影响。该研究计划旨在通过预测金属-生物界面的反应机制和速率来提高生物医学材料及其使用的安全性，例如用于纳米医学应用的金属植入材料和金属纳米颗粒。这些金属器械的腐蚀机制取决于其成分、设计、制造和患者的感染状况，必须了解这些机制才能实现最佳应用。