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NMR spectroscopy in brain organoids: identifying neurochemical and gene regulatory network signatures of the healthy and Alzheimer's Disease brain

NMR spectroscopy in brain organoids: identifying neurochemical and gene regulatory network signatures of the healthy and Alzheimer's Disease brain
大脑类器官中的核磁共振波谱:识别健康大脑和阿尔茨海默病大脑的神经化学和基因调控网络特征
批准号:
462336
负责人:
Near Jamie
金额:
$68.55万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-03-01 至 2027-03-01

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中文摘要
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英文摘要
Recent innovations in neuroscience have led to the development of human-derived 'mini-brains', also known as cerebral organoids. These self-organizing, three-dimensional clusters of human brain tissue can grow to 2-3 mm in diameter, and accurately mimic
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Prize 202203PJT - NMR spectroscopy in brain organoids: identifying neurochemical and gene regulatory network signatures of the healthy and Alzheimer's Disease brain
Development of dynamic 1H MRSI for the assessment of impaired brain glucose metabolism in patients with early Alzheimer's Disease
  • 批准号:
    402789
  • 项目类别:
    Operating Grants
  • 资助金额:
    $56.29万
  • 财政年份:
    2019
  • 负责人:
    Near Jamie
  • 依托单位:
Longitudinal neuroimaging of disease progression and treatment in rodent models of Alzheimer's Disease
国内基金
海外基金
新型F-18标记香豆素衍生物PET探针的研制及靶向Alzheimer's Disease 斑块显像研究
  • 批准号:
    81000622
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    20.0万元
  • 批准年份:
    2010
  • 负责人:
    梁胜
  • 依托单位:
阿尔茨海默病(Alzheimer's disease,AD)动物模型构建的分子机理研究
  • 批准号:
    31060293
  • 项目类别:
    地区科学基金项目
  • 资助金额:
    26.0万元
  • 批准年份:
    2010
  • 负责人:
    郭亚芬
  • 依托单位:
跨膜转运蛋白21(TMP21)对引起阿尔茨海默病(Alzheimer'S Disease)的γ分泌酶的作用研究