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Role of YAP and TAZ in Acute Myeloid Leukemia

Role of YAP and TAZ in Acute Myeloid Leukemia
YAP 和 TAZ 在急性髓系白血病中的作用
批准号:
462899
负责人:
Bremner Rod
金额:
$65.76万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-03-01 至 2027-03-01

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中文摘要
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英文摘要
Acute Myeloid Leukemia (AML) typically responds well to initial therapies, but relapse is common due to drug resistance. AML cells in the circulating blood are usually cleared well, but resistant cells remain in the bone marrow. How the bone marrow cont
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Dissecting the Tumor Suppressor Function of YAP in Neural and Neuroendocrine Cancers
  • 批准号:
    452608
  • 项目类别:
    Operating Grants
  • 资助金额:
    $73.84万
  • 财政年份:
    2021
  • 负责人:
    Bremner Rod
  • 依托单位:
The Single Cell Biology of Context-Specific Responses to Loss of the RB Tumor Suppressor Gene
Resistance to established and new RET oncogene inhibitors
Opposite roles of MYCN and YAP in cancer initiation