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Mechanisms regulating the outgrowth of initiated cells in the mammal

Mechanisms regulating the outgrowth of initiated cells in the mammal
调节哺乳动物起始细胞生长的机制
批准号:
211145
负责人:
Bremner Rod
金额:
$77.11万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-09-01 至 2015-09-01

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中文摘要
翻译
当细胞获得允许其异常生长的基因缺陷时,就会发生癌症。突变细胞分裂产生更多突变,增加了细胞获得第二缺陷的机会,使其更具侵略性。这一过程可以继续下去,直到一个
英文摘要
Cancer arises when a cell acquires a gene defect that allows it to grow abnormally. The mutant cell divides to produce more mutants increasing the chance of a cell acquiring a second defect, making it more aggressive. This process can continue until a let
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Role of YAP and TAZ in Acute Myeloid Leukemia
Dissecting the Tumor Suppressor Function of YAP in Neural and Neuroendocrine Cancers
  • 批准号:
    452608
  • 项目类别:
    Operating Grants
  • 资助金额:
    $73.84万
  • 财政年份:
    2021
  • 负责人:
    Bremner Rod
  • 依托单位:
The Single Cell Biology of Context-Specific Responses to Loss of the RB Tumor Suppressor Gene
Resistance to established and new RET oncogene inhibitors
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