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Extracellular glutamate dynamics exhibit synapse asymmetry in Alzheimer disease

Extracellular glutamate dynamics exhibit synapse asymmetry in Alzheimer disease
细胞外谷氨酸动力学在阿尔茨海默病中表现出突触不对称性
批准号：
468779
负责人：
Parsons Matthew P
金额：
$58.52万
依托单位：
Memorial University of Newfoundland
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2022
资助国家：
加拿大
项目状态：
未结题
起止时间：
2022-09-01 至 2027-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=468779&lang=en
关键词：
Electrophysiology Glutamate Imaging Glutamate Receptors Glutamate Uptake Neurotransmission Synaptic Plasticity

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英文摘要
We are quite literally defined by our brain cells and their ability to communicate with each other. All of the memories and experiences that make us who we are rely on efficient communication between brain cells. When this communication fails, as is seen
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Preserving synaptic function following gene-silencing therapy in Huntington disease: mechanisms and specificity requirements
  • 批准号：
    390414
  • 项目类别：
    Operating Grants
  • 资助金额：
    $60.75万
  • 财政年份：
    2018
  • 负责人：
    Parsons Matthew P
  • 依托单位：
    Memorial University of Newfoundland
Potential roadblocks to Huntington disease therapy: Exploring the side effects of huntingtin knock-down on synaptic physiology
  • 批准号：
    301142
  • 项目类别：
    Fellowship Programs
  • 资助金额：
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  • 财政年份：
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  • 负责人：
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  • 依托单位：
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海外基金