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Understanding the role of eIF4A in AML progression and relapse

Understanding the role of eIF4A in AML progression and relapse
了解 eIF4A 在 AML 进展和复发中的作用
批准号:
470093
负责人:
Mercier François
金额:
$67.71万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-09-01 至 2027-09-01

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中文摘要
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英文摘要
Acute myeloid leukemia (AML) is an aggressive cancer of the blood system that affects approximately 2000 Canadians every year. Over the last decade, great advances have been made in understanding the changes in the DNA of the blood cells that cause AML. H
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Deciphering the role of the E3 ubiquitin ligase HERC1 in the chemotherapy response of acute myeloid leukemia.
Identification of in vivo regulators of leukemic growth.
Identification of signaling pathways driving leukemic stem cell fitness in murine models of leukemia development
  • 批准号:
    277921
  • 项目类别:
    Fellowship Programs
  • 资助金额:
    $13.66万
  • 财政年份:
    2013
  • 负责人:
    Mercier François
  • 依托单位:
Identification of cell adhesion factors implicated in leukemic cell survival
  • 批准号:
    197110
  • 项目类别:
    Fellowship Programs
  • 资助金额:
    $13.66万
  • 财政年份:
    2009
  • 负责人:
    Mercier François
  • 依托单位:
海外基金