Regulation of p53-dependent apoptosis by Akt/PKB in C. elegans

Akt/PKB 对线虫中 p53 依赖性细胞凋亡的调节

• 批准号: 177867
• 负责人: Derry William B
• 金额: $ 7.29万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-09-01 至 2009-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=177867&lang=en
• 关键词: Apoptosis; Biochemistry; Cancer; Cell Biology; Chemotherapy; Genetics

Adult organisms must maintain a relatively constant number of cells by sustaining a critical balance between cell division and cell death. If this intricate balancing act is tipped to favour too much cell survival an organism can develop tumors. Genes t

成年生物体必须通过维持细胞分裂和增殖之间的关键平衡来维持相对恒定的细胞数量。 细胞死亡 如果这种复杂的平衡行为倾向于过多的细胞存活，有机体就会发展成肿瘤。 基因t