Age-associated metabolic regulation of anti-tumor immunity

抗肿瘤免疫的年龄相关代谢调节

• 批准号: 471340
• 负责人: Han Seong Jun
• 金额: $ 10.2万
• 依托单位: Harvard Medical School (Boston, Massachusetts)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-09-01 至 2024-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=471340&lang=en
• 关键词: Aging; Cancer Immunotherapy; Immune Regulation; Immune-Metabolism; T Cells

The human population is aging at an unprecedented rate. Although aging is the most well-known risk factor for the development of cancer, pre-clinical models of immuno-oncology predominantly rely on immunocompetent young hosts which fundamentally differ fr

人口正在以前所未有的速度老龄化。尽管衰老是癌症发展的最著名的危险因素，但免疫肿瘤学的临床前模型主要依赖于免疫活性的年轻宿主，其与免疫系统的免疫功能有根本的不同。