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Investigating a novel immunomodulatory molecule in checkpoint inhibition of T cells

Investigating a novel immunomodulatory molecule in checkpoint inhibition of T cells
研究 T 细胞检查点抑制中的新型免疫调节分子
批准号：
469797
负责人：
Melichar Heather
金额：
$59.07万
依托单位：
CIUSSS Est-de-l'Ile-de- Montral-Maisonneuve Rosemont
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2022
资助国家：
加拿大
项目状态：
未结题
起止时间：
2022-09-01 至 2027-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=469797&lang=en
关键词：
B1 Cells Co-Signaling Molecules Infection Protein-Protein Interaction Screen T Cells Tumor Necrosis Factor Receptor Tumors Vaccination

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中文摘要
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英文摘要
T cells, a subset of immune cells, are able to identify and eliminate cancerous or infected target cells. T cells recognize small protein fragments, termed 'antigens', from mutated proteins or foreign invaders through a molecule called the T cell receptor
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会议论文
Montreal Immunology Meetings Symposium: Immunological Memory of Innate and Adaptive Immune Cells
  • 批准号：
    487813
  • 项目类别：
    Miscellaneous Programs
  • 资助金额：
    $0.73万
  • 财政年份：
    2023
  • 负责人：
    Melichar Heather
  • 依托单位：
    McGill University
Regulation of thymic selection thresholds and their role in establishing T cell function
Determining cause and effect: dynamic T cell receptor signaling during thymic selection
Determining cause and effect: dynamic T cell receptor signaling during thymic selection