Investigating a novel immunomodulatory molecule in checkpoint inhibition of T cells

研究 T 细胞检查点抑制中的新型免疫调节分子

• 批准号: 469797
• 负责人: Melichar Heather
• 金额: $ 59.07万
• 依托单位: CIUSSS Est-de-l'Ile-de- Montral-Maisonneuve Rosemont
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-09-01 至 2027-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=469797&lang=en
• 关键词: B1 Cells; Co-Signaling Molecules; Infection; Protein-Protein Interaction Screen; T Cells; Tumor Necrosis Factor Receptor; Tumors; Vaccination

T cells, a subset of immune cells, are able to identify and eliminate cancerous or infected target cells. T cells recognize small protein fragments, termed 'antigens', from mutated proteins or foreign invaders through a molecule called the T cell receptor

T细胞是免疫细胞的一个子集，能够识别和消除癌细胞或受感染的靶细胞。T细胞通过一种称为T细胞受体的分子从突变蛋白质或外来入侵者中识别小的蛋白质片段，称为“抗原”