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Determining cause and effect: dynamic T cell receptor signaling during thymic selection

Determining cause and effect: dynamic T cell receptor signaling during thymic selection
确定因果关系：胸腺选择过程中的动态 T 细胞受体信号传导
批准号：
320345
负责人：
Melichar Heather
金额：
$47.21万
依托单位：
CIUSSS Est-de-l'Ile-de- Montral-Maisonneuve Rosemont
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2015
资助国家：
加拿大
项目状态：
已结题
起止时间：
2015-03-01 至 2020-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=320345&lang=en
关键词：
Negative Selection Organotypic Culture Positive Selection Regulatory T Cell T Cell Receptor Signaling Thymus Tissue Restricted Antigens Two-Photon Microscopy

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中文摘要
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英文摘要
The immune system is composed of specialized cell types, each of which plays a unique role in combating disease. One of these cell subsets, T cells, develops in the thymus and plays an important function in recognizing, and eliminating, abnormal cells suc
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会议论文
Montreal Immunology Meetings Symposium: Immunological Memory of Innate and Adaptive Immune Cells
  • 批准号：
    487813
  • 项目类别：
    Miscellaneous Programs
  • 资助金额：
    $0.73万
  • 财政年份：
    2023
  • 负责人：
    Melichar Heather
  • 依托单位：
    McGill University
Investigating a novel immunomodulatory molecule in checkpoint inhibition of T cells
Regulation of thymic selection thresholds and their role in establishing T cell function
Determining cause and effect: dynamic T cell receptor signaling during thymic selection
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