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Defining the role of fetal reprogramming in the gut epithelium in health and disease.

Defining the role of fetal reprogramming in the gut epithelium in health and disease.
定义胎儿肠道上皮重编程在健康和疾病中的作用。
批准号：
469443
负责人：
Gregorieff Alex
金额：
$54.62万
依托单位：
Research Institute of the McGill University Health Centre
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2022
资助国家：
加拿大
项目状态：
未结题
起止时间：
2022-09-01 至 2027-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=469443&lang=en
关键词：
Colorectal Cancer Conditional Ko Mice Fetal Gut Development Fetal Reprogramming Hippo Signaling Intestinal Regeneration Intestinal Stem Cell Organoids Tgf-Beta Signaling Wnt Signaling

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中文摘要
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英文摘要
During embryonic development, pluripotent stem cells play a fundamental role in creating the wide variety of tissue types in our bodies. More specialised stem cells are also critical in ensuring that tissues maintain an ability to repair themselves follow
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Role of Hippo signaling in myofibroblasts during gut regeneration and tumorigenesis.
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