Metabolic optimization of Tregs to attenuate anti-islet immunity

Tregs 的代谢优化可减弱抗胰岛免疫力

• 批准号: 472188
• 负责人: Tuomela Karoliina
• 金额: $ 9.83万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-10-01 至 2025-10-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=472188&lang=en
• 关键词: Adaptive Immunity; Autoimmunity; Cell Therapy; Diabetes; Metabolism; Regulatory T Cell

Diabetes is an autoimmune disease in which the immune system destroys insulin-producing cells in the pancreas. Insulin production can be restored by transplanting islets, which contain insulin-producing cells, either from deceased donors or made from stem

糖尿病是一种自身免疫性疾病，其中免疫系统破坏胰腺中的胰岛素产生细胞。胰岛素的产生可以通过移植胰岛来恢复，胰岛含有产生胰岛素的细胞，这些细胞来自已故的捐赠者或由干细胞制成。