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Defining the critical genomic dependencies of non-V600 BRAF mutant tumors to optimize targeted therapeutic strategies

Defining the critical genomic dependencies of non-V600 BRAF mutant tumors to optimize targeted therapeutic strategies
定义非 V600 BRAF 突变肿瘤的关键基因组依赖性,以优化靶向治疗策略
批准号:
472038
负责人:
Riaud Melody
金额:
$9.83万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-10-01 至 2025-10-01

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英文摘要
Tumor growth is mediated by the MAPK signaling pathway, involving the BRAF protein. During tumor development, mutations on proteins are commonly identified in advanced cancers and their prevalence varies by cancer type to promote tumor progression. BRAF i
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