Origins of childhood asthma: Role of viral infections on lung and immunological dysfunction using a translational bioinformatics approach

儿童哮喘的起源：使用转化生物信息学方法研究病毒感染对肺和免疫功能障碍的作用

• 批准号: 477427
• 负责人: Medeleanu Maria
• 金额: $ 7.65万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-10-01 至 2025-10-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=477427&lang=en
• 关键词: Childhood Asthma; Endotyping; Generalized Estimating Equations; Hierarchial Clustering/Unsupervised Machine Learning; Immune Protein Biomarkers; Nasal Microbiome; Precision Medicine; Pulmonary Function Tests; Respiratory Viruses; Translational Bioinformat

10% of children under 14 have asthma, making it the most common childhood chronic disease and the leading cause for hospitalization of Canadian children. Childhood-onset asthma is chronic and complex but can best be described by two disease processes: lun

10%的14岁以下儿童患有哮喘，使其成为最常见的儿童慢性疾病，也是加拿大儿童住院的主要原因。儿童期发作的哮喘是慢性和复杂的，但可以最好地描述为两个疾病过程：肺