New nickel compounds for sustainable catalysis

用于可持续催化的新型镍化合物

• 批准号: 571328-2021
• 负责人: Drover, MarcusM
• 金额: $ 1.82万
• 依托单位: University of Windsor
• 依托单位国家: 加拿大
• 项目类别: Alliance Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=748384
• 关键词: New; nickel; compounds; sustainable; catalysis

The ligands that are attached to a transition metal complex have a profound influence on its reactivity. The relationship between ligand structure and the reactivity of the corresponding complex is not often well understood, and there are many opportunities to develop new reactivity by examining new ligand scaffolds. This project will develop a thorough understanding of how different ligands can be used to achieve new reactivity and selectivity in the field of nickel catalysis by applying Professor Drover's expertise in organometallic synthesis and ligand design, and Dr Nelson's expertise in physical (in)organic chemistry and computational modelling. The aim is to do so via a series of studies examining key steps, such as oxidative addition and transmetalation, that are crucial to widely-used reactions. This project will also make use of a set of Lewis acid-functionalised ligands that have been pioneered by Professor Drover.

连接到过渡金属络合物上的配体对其反应活性有深远的影响。配体结构和相应络合物的反应性之间的关系往往不是很清楚，有很多机会通过检查新的配体支架来开发新的反应性。这个项目将通过应用Drover教授在有机金属合成和配体设计方面的专业知识，以及Nelson博士在物理(In)有机化学和计算模型方面的专业知识，深入了解如何在镍催化领域使用不同的配体来实现新的反应性和选择性。其目的是通过一系列研究来检验关键步骤，如氧化加成和转金属反应，这些步骤对广泛使用的反应至关重要。该项目还将利用Drover教授首创的一组Lewis酸功能化配体。