New nickel compounds for sustainable catalysis

用于可持续催化的新型镍化合物

• 批准号: 571328-2021
• 负责人: Drover, MarcusM
• 金额: $ 1.82万
• 依托单位: University of Windsor
• 依托单位国家: 加拿大
• 项目类别: Alliance Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=748384
• 关键词: New; nickel; compounds; sustainable; catalysis

The ligands that are attached to a transition metal complex have a profound influence on its reactivity. The relationship between ligand structure and the reactivity of the corresponding complex is not often well understood, and there are many opportunities to develop new reactivity by examining new ligand scaffolds. This project will develop a thorough understanding of how different ligands can be used to achieve new reactivity and selectivity in the field of nickel catalysis by applying Professor Drover's expertise in organometallic synthesis and ligand design, and Dr Nelson's expertise in physical (in)organic chemistry and computational modelling. The aim is to do so via a series of studies examining key steps, such as oxidative addition and transmetalation, that are crucial to widely-used reactions. This project will also make use of a set of Lewis acid-functionalised ligands that have been pioneered by Professor Drover.

连接到过渡金属络合物的配体对其反应性具有深远的影响。配体结构与相应复合物的反应性之间的关系经常被良好理解，并且有很多机会通过检查新的配体支架来发展新的反应性。该项目将通过应用Drover教授在有机金属合成和配体设计方面的专业知识以及尼尔森博士在物理（IN）有机化学和计算建模方面的专业知识，将如何使用不同的配体在镍催化领域实现新的反应性和选择性。目的是通过一系列研究对广泛使用反应至关重要的关键步骤（例如氧化添加和跨金属）进行研究。该项目还将利用一组由Drover教授开创的Lewis酸官能化的配体。