Investigating sex differences in sensory neurons in a model of Multiple Sclerosis: Implications for chronic pain in the disease.

研究多发性硬化症模型中感觉神经元的性别差异：对该疾病慢性疼痛的影响。

• 批准号: 475686
• 负责人: Maguire Aislinn
• 金额: $ 7.65万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-11-01 至 2025-11-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=475686&lang=en
• 关键词: Autoimmune Disease; Biochemistry; Cell Culture; Cellular Signaling; Cytokines; Imaging; Inflammation; Mitochondria; Pain; Sex Differences

Chronic Pain is highly prevalent in the autoimmune disease Multiple Sclerosis (MS), and women with MS tend to be affected more by chronic pain than men. Additionally, conventional pain treatment strategies are often ineffective against chronic pain in MS

慢性疼痛在自身免疫性疾病多发性硬化症（MS）中非常普遍，患有MS的女性往往比男性更容易受到慢性疼痛的影响。此外，传统的疼痛治疗策略通常对MS中的慢性疼痛无效