Structural basis of phase separation of the YTH N6-Methyladenosine RNA Binding Protein 2 (YTHDF2).

YTH N6-甲基腺苷 RNA 结合蛋白 2 (YTHDF2) 相分离的结构基础。

• 批准号: 492987
• 负责人: Lobato Vergara Rodrigo
• 金额: $ 1.27万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=492987&lang=en
• 关键词: Intrinsically Disordered Regions; M6a; Methylation; Phase Separation; Proteins; Rna; Ythdf2

Chemical modifications occur in our genetic material all the time (i.e., DNA and RNA), affecting the way our cells operate. Sometimes even causing diseases such as obesity, infertility, autoimmune diseases (e.g., diabetes), neurological diseases, and canc

我们的遗传物质（即 DNA 和 RNA）始终发生化学修饰，影响我们细胞的运作方式。有时甚至引起肥胖、不孕不育、自身免疫性疾病（如糖尿病）、神经系统疾病和癌症等疾病