Development and validation of novel XPO1 inhibitors to modulate protein metabolism
Development and validation of novel XPO1 inhibitors to modulate protein metabolism
调节蛋白质代谢的新型 XPO1 抑制剂的开发和验证
批准号：
486628
负责人：
Duverger Aziliz
金额：
$1.27万
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2022
资助国家：
加拿大
项目状态：
已结题
起止时间：
2022-12-01 至 2023-12-01
中文摘要
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英文摘要
Several neurodegenerative diseases are characterized by a proteostatic imbalance in neurons due to the accumulation of damaged and aggregated proteins . To resolve this problem, neurons use autophagy to sequester and degrade dysfunctional proteins via the
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