Role of the human telomerase insertion in fingers domain in telomerase activation at telomeres

人端粒酶插入手指结构域在端粒端粒酶激活中的作用

• 批准号: 486140
• 负责人: Pallotto Linda M
• 金额: $ 1.27万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=486140&lang=en
• 关键词: Aging; Cancer; Telomerase; Telomeres

Cancer often occurs through a loss of control at the level of cell division that allows tumours to form. This happens because the tumour cells can continuously elongate the ends of DNA strands, known as the telomeres. In contrast, most healthy cells need

癌症通常是通过细胞分裂水平的失控而发生的，这种细胞分裂水平允许肿瘤形成。这是因为肿瘤细胞可以不断延长DNA链的末端，称为端粒。相比之下，大多数健康细胞需要